Computational models of intracytoplasmic sperm injection prognosis
نویسندگان
چکیده
Intracytoplasmic sperm injection (ICSI), a procedure in which a single sperm is microinjected into an ovum, presents a difficult modeling problem highly sensitive to both underand overfitting. We modeled an ICSI data set of 528 outcomes with a variety of clinical and laboratory variates using linear and non-linear (neural computational) logistic regression methods and with linear and radial basis function support vector machines. Interestingly, depending on the threshold chosen to determine a positive outcome, investigated neural computational methods yielded similar or lower ROC AUCs than logistic regression in the test set, whereas support vector machines yielded similar or higher ROC AUCs than those of logistic regression and the investigated neural computational models.
منابع مشابه
Comparison of Intracytoplasmic Sperm Injection Outcomes between Obstructive Azoospermic Patients
متن کامل
P-41: Evaluation of CAPZA3 Expression in Infertile Individuals Undergoing Intracytoplasmic Sperm Injection
Background: CAPZA3 is one of the actin-capping proteins believed to be play an important role in controlling of actin polymerization during spermiogenesis and has been shown to be peresent in mature sperm. Immunohistochemistry showed that human CAPZA3 is localized in the neck region of ejaculated sperm, with moderate and faint signals also detected in the tail and post-acrosome region respectiv...
متن کاملEffects of Various Activators on Bovine Embryonic Development Following Intracytoplasmic Sperm Injection
The objective of this study was to compare the effectiveness of various combination activators of bovine oocyte following intracytoplasmic sperm injection (ICSI) in terms of cleavage and embryo development. Bovine ICSI oocytes were treated with a variation of treatments of combined or single activators as follows; 30 V for 15 x 2 μsec of electrical pulse +10 μg/mL cycloheximide (CHX),7% ethanol...
متن کامل